ABSTRACT
O acometimento ocular da paracoccidioidomicose é raro e quando ocorre é geralmente secundário à disseminação hematogênica. Descrição de um caso de paracococcidioidomicose multifocal em homem de 73 anos com história de trauma contuso no olho direito por pedaço de madeira e que teve como primeira manifestação clínica lesão palpebro-conjuntival. Interroga-se possível infecção primária ocular por contiguidade e alerta-se para a manifestação da doença em idade mais avançada.
Ocular involvement of paracoccidioidomycosis is rare and when it occurs it is usually secondary to hematogenic dissemination. A case of multifocal paracoccidioidomycosis in a 73 year-old male after history of blunt trauma in the right eye with a stick of wood that presented as the first clinical sign a lid-conjunctival lesion is described. The possible primary ocular infection spreading by contiguity is argued and the disease manifestation in an advanced age is highlighted.
Subject(s)
Aged , Humans , Male , Blepharitis/complications , Eye Injuries/complications , Paracoccidioidomycosis/microbiology , Wounds, Nonpenetrating/complications , Blepharitis/microbiologyABSTRACT
Se diseño un estudio doble ciego, prospectivo, longitudinal y experimental comparando la eficacia, tolerancia y toxicidad de la criprofloxacina y la tobramicina tópica al 0.3 por ciento en el tratamiento de las blefaroconjuntivitis y las queratoconjuntivitis. Se incluyeron 40 ojos en cada grupo, encontrando que ambos fármacos son igualmente efectivos para erradicar o reducir los gérmenes causantes de infección en un 95 por ciento. La ciprofloxacina dismuyó el lagrimeo y prurito en forma estadísticamente más importante (p<0.05) que la tombracina además de ser mejor tolerada y no haber provocado efectos tóxicos secundarios
Subject(s)
Humans , Male , Female , Tobramycin/administration & dosage , Tobramycin/pharmacology , Blepharitis/microbiology , Blepharitis/drug therapy , Ciprofloxacin/administration & dosage , Ciprofloxacin/pharmacology , Keratoconjunctivitis, Infectious/microbiology , Keratoconjunctivitis, Infectious/drug therapy , Anti-Bacterial Agents/pharmacology , Ophthalmic Solutions/administration & dosageABSTRACT
This study was conducted on 140 cases of chronic blepharitis, and 25 of age and sex matched normal controls. They were all evaluated ophthalmologically, bacteriologically and dermatologically. It was found that blepharitis can be classified into 5 groups: seborrheic, infective, mixed infective/seborrheic, meibomian and others. Pathogenesis of blepharitis includs various local and systemic factors. A significant role was found for external irritants, prolonged exposure to strong sun, unhyglenic surroundings, insufficient sleep and local ocular cosmetics. From this study, it was found that bacteria and fungi have no primary role in the pathogenesis of many of the cases of blehparitis even in some of the infective group